Laboratory of Synthetic Genome Biology
Developing biological engineering approaches to understand epigenetics and genome organization in C. elegans

Publications


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Total result(s) found: 19
  • Froekjaer-Jensen et al. (2016). An Abundant Class of Non-coding DNA Can Prevent Stochastic Gene Silencing in the C. elegans Germline.​ Cell.​​
Keywords:
Non-coding DNA, Transposons, Genome Defense mechanisms, C. elegans, small RNAs, Germline, Fire lab, Stanford University
  • Edelman et al. (2016). Analysis of a lin-42/period Null Allele Implicates All Three Isoforms in Regulation of Caenorhabditis elegans Molting and Developmental Timing.​ G3. 
Keywords:
heterochronic genes, lin-42, period, C. elegans, Rougvie lab, University of Minnesota.
  • Wheeler et al. (2016). Chromosome-wide mechanisms to decouple gene expression from gene dose during sex-chromosome evolution.​ Elife
Keywords:
Dosage compensation, Germline, Chromosome-wide mechanism, C. elegans, Meyer lab, University of California Berkeley
  • Froekjaer-Jensen (2015). Transposon-Assisted Genetic Engineering with Mos1-Mediated Single-Copy Insertion (MosSCI).​ Methods Molecular Biology. Book Chapter. ​​​​
Keywords:
Transgenesis, Mos1, Methods, Book Chapter
  • Froekjaer-Jensen. (2013). Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9.​ Genetics. ​
Keywords:
Review, Cas9, Genetic engineering, C. elegans, University of Utah.
  • Froekjaer-Jensen et al. (2012). Improved Mos1-mediated transgenesis in C. elegans.​ Nature Methods. ​
Keywords:
Transgenesis, Mos1, C. elegans, Jorgensen lab, University of Utah
  • Laine et al. (2011). The alpha1 subunit EGL-19, the alpha2/delta subunit UNC-36, and the beta subunit CCB-1 underlie voltage-dependent calcium currents in Caenorhabditis elegans striated muscle. Journal of Biological Chemistry.
Keywords:
Ion Channels, Voltage-gated calcium channels, muscle, C. elegans, Jospin Lab, CNRS.
  • Zeisser et al. (2011). MosSCI and gateway compatible plasmid toolkit for constitutive and inducible expression of transgenes in the C. elegans germline.​ PLoS One. 
Keywords:
Transgenesis, Mos1, Germline expression, C. elegans.
  • Froekjaer-Jensen et al. (2010). Targeted gene deletions in C. elegans using transposon excision. Nature Methods. ​
Keywords:
Transgenesis, Mos1, transposon, targeted deletion, C. elegans, Jorgensen lab, University of Utah
  • Froekjaer-Jensen and Jorgensen. (2009). Calcium: an insignificant thing.​ Nature Neuroscience. ​
Keywords:
Mini-review
  • Froekjaer-Jensen et al. (2008). Single-copy insertion of transgenes in Caenorhabditis elegans. Nature Genetics. ​
Keywords:
Transgenesis, Endogenous expression, Germline expression, Single-copy transgenes, Jorgensen Lab, University of Utah
  • Froekjaer-Jensen et al. (2008). Ammonium-acetate is sensed by gustatory and olfactory neurons in Caenorhabditis elegans. PLoS One​
Keywords:
Neuroscience, behavior, NaCl sensation, Assymetry, C. elegans, Lockery lab, University of Oregon
  • Rasmussen et al. (2007). Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment. J. Cell Sci. 
Keywords:
Potassium channels, electrophysiology, rat neurons, Olesen Lab, University of Copenhagen
  • Froekjaer-Jensen et al. (2006). Effects of voltage-gated calcium channel subunit genes on calcium influx in cultured C. elegans mechanosensory neurons. J. Neurobiology. ​​​​​
Keywords:
Neuroscience, Calcium imaging, voltage-gated calcium channels, C. elegans, University of California San Diego
  • Ortiz et al. (2006). Searching for neuronal left/right asymmetry: genomewide analysis of nematode receptor-type guanylyl cyclases. Genetics
Keywords:
Nervous system, Assymetry, microRNAs, C. elegans, Hobert Lab, Columbia University
  • ​Bianchi et al. (2004). The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation. Nature Neuroscience​
Keywords:
Mechanosensation, Neurotoxicity, Calcium imaging, C. elegans, Schafer Lab, Driscoll Lab
  • Chang et al. (2004). MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.​ Nature.​
Keywords:
MicroRNAs, C. elegans, Assymetry, Nervous system, transcription factors, Hobert Lab, Columbia University
  • Suzuki et al. (2003). In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation. Neuron
Keywords:
C. elegans, Calcium imaging, genetic encoded sensors, neuroscience, Schafer Lab, University of California San Diego
  • Grunnet et al. (2001). Pharmacological modulation of SK3 channels. ​Neuropharmacology.​​​
Keywords:
SK channel, afterhyperpolarization, pharmacology, Olesen Lab, University of Copenhagen