Publications

A balance between silencing foreign DNA and protecting self in Caenorhabditis elegans

Current Opinion in Systems Biology Review Year: 2019

Authors: Christian Frøkjær-Jensen

piRNA
Small RNAs
Genome Defense mechanisms
Epigenetics
Heterochromatin

Assessment and Maintenance of Unigametic Germline Inheritance for C. elegans.

Developmental Cell Journal Article Year: 2019

Authors: Artiles KL, Fire AZ, Christian Frøkjær-Jensen

C. elegans
Genetic engineering
Inheritance
Mitosis
Mosaic
Non-Mendelian
Synthetic Biology

The Caenorhabditis elegans Transgenic Toolbox.

Genetics Review Year: 2019

Authors: Nance J, Christian Frøkjær-Jensen

SapTrap Assembly of Caenorhabditis elegans MosSCI Transgene Vectors.

G3 (Bethesda) Journal Article Year: 2020

Authors: Fan X, De Henau S, Feinstein J, Miller SI, Han B, Christian Frøkjær-Jensen, Griffin EE

An Abundant Class of Non-coding DNA Can Prevent Stochastic Gene Silencing in the C. elegans Germline.

Cell Journal Article Year: 2016

Authors: Christian Frøkjær-Jensen, Jain N, Hansen L, Davis MW, Li Y, Zhao D, Rebora K, Millet JRM, Liu X, Kim SK, Dupuy D, Jorgensen EM, Fire AZ

Non-coding DNA
Transposons
Genome Defense mechanisms
C. elegans
Small RNAs
Germline
Fire lab
Stanford University

Analysis of a lin-42/period Null Allele Implicates All Three Isoforms in Regulation of Caenorhabditis elegans Molting and Developmental Timing.

G3 (Bethesda) Journal Article Year: 2016

Authors: Edelman TL, McCulloch KA, Barr A, Christian Frøkjær-Jensen, Jorgensen EM, Rougvie AE

Heterochronic genes
Lin-42, period
C. elegans
Rougvie lab
University of Minnesota

Chromosome-wide mechanisms to decouple gene expression from gene dose during sex-chromosome evolution.

Elife Journal Article Year: 2016

Authors: Wheeler BS, Anderson E, Christian Frøkjær-Jensen, Bian Q, Jorgensen EM, Meyer BJ

Dosage compensation
Germline
Chromosome-wide mechanism
C. elegans
Meyer lab
University of California Berkeley

Transposon-Assisted Genetic Engineering with Mos1-Mediated Single-Copy Insertion (MosSCI).

Book Chapter Methods Molecular Biology Year: 2015

Authors: Christian Frøkjær-Jensen

Transgenesis
Mos1
Methods
Book Chapter

Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9.

Genetics Review Year: 2013

Authors: Christian Frøkjær-Jensen

Review
Cas9
Genetic engineering
C. elegans
University of Utah

Improved Mos1-mediated transgenesis in C. elegans.

Journal Article Nature Methods Year: 2012

Authors: Christian Frøkjær-Jensen, Davis MW, Ailion M, Jorgensen EM

Transgenesis
Mos1
C. elegans
Jorgensen Lab
University of Utah

The alpha1 subunit EGL-19, the alpha2/delta subunit UNC-36, and the beta subunit CCB-1 underlie voltage-dependent calcium currents in Caenorhabditis elegans striated muscle.

J. Biol Chem Journal Article Year: 2011

Authors: Lainé V, Frøkjaer-Jensen C, Couchoux H, Jospin M

Ion Channels
Voltage-gated calcium channels
Muscle
C. elegans
Jospin Lab
CNRS

MosSCI and gateway compatible plasmid toolkit for constitutive and inducible expression of transgenes in the C. elegans germline.

Journal Article PLoS One Year: 2011

Authors: Zeiser E, Frøkjaer-Jensen C, Jorgensen E, Ahringer J

Transgenesis
Mos1
Germline expression
C. elegans

Targeted gene deletions in C. elegans using transposon excision.

Journal Article Nature Methods Year: 2010

Authors: Frøkjaer-Jensen C, Davis MW, Hollopeter G, Taylor J, Harris TW, Nix P, Lofgren R, Prestgard-Duke M, Bastiani M, Moerman DG, Jorgensen EM

Transgenesis
Mos1
Transposon
Targeted deletion
C. elegans
Jorgensen Lab
University of Utah

Calcium: an insignificant thing.

Mini-review Nature Neuroscience Year: 2009

Authors: Frøkjaer-Jensen C, Jorgensen EM

Mini-review

Single-copy insertion of transgenes in Caenorhabditis elegans.

Journal Article Nature Genetics Year: 2008

Authors: Frøkjaer-Jensen C, Davis MW, Hopkins CE, Newman BJ, Thummel JM, Olesen SP, Grunnet M, Jorgensen EM

Transgenesis
Endogenous expression
Germline expression
Single-copy transgenes
Jorgensen Lab
University of Utah

Ammonium-acetate is sensed by gustatory and olfactory neurons in Caenorhabditis elegans.

Journal Article PLoS One Year: 2008

Authors: Frøkjaer-Jensen C, Ailion M, Lockery SR

Neuroscience
Behavior
NaCl sensation
Assymetry
C. elegans
Lockery lab
University of Oregon

Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

J Cell Science Journal Article Year: 2007

Authors: Rasmussen HB, Frøkjaer-Jensen C, Jensen CS, Jensen HS, Jørgensen NK, Misonou H, Trimmer JS, Olesen SP, Schmitt N

Potassium channels
Electrophysiology
Rat neurons
Olesen Lab
University of Copenhagen

Effects of voltage-gated calcium channel subunit genes on calcium influx in cultured C. elegans mechanosensory neurons.

J Neurobiology Journal Article Year: 2006

Authors: Frøkjaer-Jensen C, Kindt KS, Kerr RA, Suzuki H, Melnik-Martinez K, Gerstbreih B, Driscol M, Schafer WR.

Neuroscience
Calcium imaging
Voltage-gated calcium channels
C. elegans
University of California San Diego

Searching for neuronal left/right asymmetry: genomewide analysis of nematode receptor-type guanylyl cyclases.

Genetics Journal Article Year: 2006

Authors: Ortiz CO, Etchberger JF, Posy SL, Frøkjaer-Jensen C, Lockery S, Honig B, Hobert O

Nervous system
Assymetry
MicroRNAs
C. elegans
Hobert Lab
Columbia University

The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation.

Journal Article Nature Neuroscience Year: 2004

Authors: Bianchi L, Gerstbrein B, Frøkjaer-Jensen C, Royal DC, Mukherjee G, Royal MA, Xue J, Schafer WR., Driscoll M

Mechanosensation
Neurotoxicity
Calcium imaging
C. elegans
Schafer Lab
Driscoll Lab

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.

Journal Article Nature Year: 2004

Authors: Chang S, Johnston RJ Jr, Frøkjaer-Jensen C, Lockery S, Hobert O

MicroRNAs
C. elegans
Assymetry
Nervous system
Transcription factors
Hobert Lab
Columbia University

In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation.

Journal Article Neuron Year: 2003

Authors: Suzuki H, Kerr R, Bianchi L, Frøkjaer-Jensen C, Slone D, Xue J, Gerstbrein B, Driscoll M, Schafer WR.

C. elegans
Calcium imaging
Genetic encoded sensors
Neuroscience
Schafer Lab
University of California San Diego

Pharmacological modulation of SK3 channels

Journal Article Neuropharmacology Year: 2001

Authors: Morten Grunnet, Thomas Jespersen, Kamilla Angelo, Christian Frøkjær-Jensen, Dan A Klaerke, Søren-Peter Olesen, Bo Skaaning Jensen

SK channel
Afterhyperpolarization
Pharmacology
Olesen Lab
University of Copenhagen

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